The tobacco barn is made of chestnut wood, which is lightweight, strong, sturdy, and highly resistant to decay. The chestnut tobacco barn came to Historic Collinsville from the nearby Vertrees farm. It was used solely for air-cured burley tobacco — a cash crop that generated great wealth for 19th-Century Montgomery County. Tobacco also connected Clarksville with locations around the globe where it was exported. The air-flow openings between the logs of the barn helped cure the tobacco, which was not fire-cured at any time. Currently, the barn is used for a variety of activities and is available for event rentals.